Could vitamin D be key to slowing human aging? Here’s what the latest research says
Recent research questions the effectiveness of vitamin D supplements in the fight against aging, highlighting the complexities and shortcomings in understanding the effects of this supplement.
Discovering the secret to aging gracefully has long fascinated many, hoping that a simple solution like a daily pill could turn back time.
Among the potential candidates is vitamin D, which stands out for its role in maintaining muscle and bone health, key parts of the human body that deteriorate with age.
Research shows a link between vitamin D deficiency and an increased risk of age-related problems, such as muscle wasting and falls.
However, addressing the question of whether vitamin D supplements can prevent such deterioration requires navigating complex scientific terrain. A recent scientific review by Italian scientists sheds light on this topic, dissecting the complex biological processes that underlie aging. Carmelinda Ruggiero, a specialist in geriatrics from the Italian University of Perugia, emphasizes the complexity of these processes. The characteristics of aging are incredibly complex and interrelated, says Ruggiero.
Human trials are rare, conflicting, or inconclusive
While vitamin D supplementation has long been prescribed for conditions such as osteoporosis, recent clinical trials cast doubt on its effectiveness in preventing age-related bone loss and fractures in otherwise healthy individuals.
Ruggiero’s team delved into observational studies and clinical trials regarding vitamin D’s potential effects on signs of aging, finding a lack of evidence in humans and a primary reliance on animal models.
The results of their work were published in the journal Nutrients.
Although some studies suggest vitamin D’s potential to slow epigenetic aging and reduce DNA damage, its effects on telomere length (the structure at the ends of chromosomes) remain inconclusive. In addition, determining the optimal dose and timing of supplementation has proven challenging due to sparse and conflicting human trials. There are also concerns about the safety of high doses of vitamin D, which can be harmful, and interactions with other medications.
A holistic approach to lifestyle
Although increasing vitamin D intake seems intuitive, experts caution against over-reliance on supplements, advocating for holistic lifestyle approaches.
Ruggiero and her colleagues highlight the gap between research findings and practical applications, urging a careful approach. Despite interest in the potential role of vitamin D in human longevity, translating research into tangible benefits remains a distant goal.
Finally, the review by Italian scientists highlights the need for further research to unlock the full potential of vitamin D in the aging process.
Source: Science Alert
